Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0382777
PubChem CID
Molecular Formula
C22H45BrN2
Molecular Weight
417.52 g/mol
Synonyms/Alias
[62634-16-6; 4-Aza-1-azoniabicyclo[2.2.2]octane; 1-hexadecyl-; bromide; 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane Bromide; DTXSID50469441]
InChI Key
BVWUAKNLSMADAT-UHFFFAOYSA-M
InChI
InChI=1S/C22H45N2.BrH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-24-20-16-23(17-21-24)18-22-24;/h2-22H2...
IUPAC Name
1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane;bromide
CAS Number
62634-16-6

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

70 70 0 0 0 0 0 0 0 0999 V2000
9.8619 -2.7671 -1.0997 C 0 0 0 0 0 0 0 0 0 0 0 0
8.4786 -2.1221 -1.1039 C 0 0 0 0 0 0 0 0 0 0 0 0
8.4588 -0.850...

Experimental Data

Activity Data

Target Ion Channel
Voltage-gated potassium channel subfamily C member 4
Uniprot Accession Number
Function
Blocker
Species
Homo sapiens (Human)
IC50
IC50: 600 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−80 mV mV
Temperature
22–25 °C
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
25
Rotatable Bonds
15
logP
2.6177
Complexity
106.4804
TPSA (Ų)
3.24
H-Bond Donors
0
H-Bond Acceptors
1
Ring Count
3
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